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Cosmelan is a renowned skin treatment designed to combat hyperpigmentation and various forms of skin discoloration.

Treatment & one month home care: £850 Book this treatment
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Developed by Mesoestetic, a leading pharmaceutical company, it's a professional-grade solution trusted by dermatologists worldwide. The treatment's efficacy lies in its multifaceted approach, combining both in-office applications and at-home maintenance.

Cosmelan works by inhibiting melanin production, targeting dark spots, melasma, and other pigmentation issues. With a track record of success, it's a sought-after option for individuals seeking a comprehensive and tailored approach to achieving a more even, radiant complexion.

Cosmelan operates through a two-step process, beginning with an in-clinic application of the Cosmelan 1 mask, which contains a blend of powerful depigmenting agents.

These ingredients, including kojic acid, phytic acid, and azelaic acid, work together to inhibit the enzyme responsible for melanin production. By slowing down this process, Cosmelan effectively reduces the appearance of dark spots and uneven pigmentation.

Following the initial treatment, patients continue the process at home using the Cosmelan 2 cream. This product contains additional depigmenting agents, along with soothing and hydrating ingredients to support skin recovery. Consistent use of Cosmelan 2 is crucial for maintaining and maximising the treatment's benefits.

Over the course of a few weeks, the combination of in-clinic and at-home treatments leads to a noticeable reduction in hyperpigmentation.

The skin's tone becomes more even, with dark spots and discolouration gradually fading. It's worth noting that Cosmelan is highly customisable, allowing for adjustments in intensity to suit individual skin types and concerns.

This dual-action approach sets Cosmelan apart as a powerful solution for those struggling with skin pigmentation issues. It's particularly favoured by dermatologists and skincare professionals for its efficacy and ability to deliver significant, long-lasting results.



Cosmelan is suitable for individuals with hyperpigmentation, melasma, sunspots, and other forms of skin discoloration. It's effective for various skin types and tones, making it a versatile treatment option for those seeking to address pigmentation issues and achieve a more even complexion.


Cosmelan is considered safe when administered by a qualified skincare professional. Its formulation is carefully designed to minimise potential side effects. However, like any treatment, there may be rare instances of mild irritation or sensitivity. Consulting Ambra’s experienced practitioners ensures proper application and reduces any associated risks.


During the in-clinic application, Cosmelan may cause a tingling or warm sensation. However, any discomfort is typically brief and well-tolerated. The procedure is generally considered to be minimally painful, and any temporary sensations subside quickly.


Cosmelan may lead to mild side effects, including temporary redness, dryness, and peeling. These effects are generally short-lived and can be managed with post-treatment care. Severe reactions are uncommon when administered by a trained practitioner.


Although patients can generally continue their usual daily tasks following a Cosmelan treatment, some redness, dryness, and peeling may be experienced for up to 5 days. Makeup can be applied after the first few days to conceal any residual effects.


Treatment & one month home care: £850

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Treatment starting from £850

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Used Dr Maryam McMillan for a few years now. She is AMAZING. Would not trust anyone else with my face now. So happy. Feel the most confident I’ve ever felt. Prices are good and service even better x

Five stars Callie Jayne 5 months ago

I went to see Dr McMillan for the first time about a year ago so she could revise some badly done under eye filler NOT DONE BY DR MCMILLAN, and she’s done the most fantastic job i had terrible anxiety from the previous injector and was very nervous, I did so much research but decided to go ahead with Dr McMillan as she was so reassuring and honest with it all

Five stars Mel 5 months ago

Having visited many clinics across the world, Ambra Aesthetic provides the highest in skin care. The staff are incredibly professional & knowledgeable. They always tailor the treatments according to your skin type. They are the best.

Five stars Alice Katz 2 months ago

I would highly recommend Maryam and her team at Ambra Aesthetic clinic, my husband had dental treatment with straightening and whitening of his teeth and the results are amazing. I have also had various treatments and we are both very pleased with the service, kindness shown and professionalism. Thank you Ambra. See you soon.

Five stars Liza Pluto 2 months ago

Ambra Aesthetics are the place to go to for professional, friendly service. You don’t need to go to Harley Street. Dr M and her team are all experts and really take care of you giving the best treatments and advice. Sam on the front desk is a dream. In lots of places the staff can look scary from doing too much but Ambra you can tell it’s all about discrete subtle tweakments. . Don’t hesitate to go!

Five stars Dan 2 months ago

Such friendly, professional service! Dr Maryam is brilliant and everyone at the clinic is so helpful. Ambra is excellent at Profilho, dermal fillers and Hydrafacial. It is like a top Central London aesthetic clinic on your doorstep – only with easy parking and lovely people!

Five stars Sue Cipin 2 months ago